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An article published on The American Journal on Addictions stated that expectant women who were addicted to opioids were strongly considering antagonist treatment, especially one that involves the use of naltrexone to combat their alcohol abuse disorder.

Using two separate drugs to shed pounds can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with fat loss and the people who go through it you ought to err assisting caution and let the FDA do its job and demand some study be done so that the public is aware of the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to earn money and that they would say almost anything to keep people on the medications.

Researchers found that participants taking this drug to get a year, dropped a few pounds within four weeks and have kept the load off through the 56 weeks with the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which are made up of several active ingredient, which can make them far better and safer.

Combo-pilling is the newest fad or even better the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is now popular is the fact that by right now there aren't any long term prescription slimming capsules that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug may also raise hypertension and heart rate, and mustn't be used in individuals with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and pulse rate and must 't be used in patients with uncontrolled high blood pressure, and also by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients towards the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.


Approving a drug with this many potentially lethal negative effects is inconsistent using the mission statement of the FDA. The power with the drug manufacturing lobby is blatantly evident in the approval of countless drugs requiring 'post-marketing' studies which are clearly significant to overall drug safety within the US.